Epidermodysplasia Verruciformis, also known as Tree Bark Syndrome, is an inherited skin disorder characterized by eruptions of wart-like lesions that may occur anywhere on the body. One type of lesions are reddish brown and have scaly surfaces and irregular borders; while the second type are seen on sun-exposed skin and are often slightly raised, brown colored lesions resembling tree bark.
These lesions are caused by infection with a subtype of human papillomavirus (HPV). In general, this virus does not cause any lesions but in people with Epidermodysplasia Verruciformis, the virus causes these lesions. A major concern for these patients is that the disorder may turn into skin cancers. There is no known cure for this disorder. It is managed through medication, surgery and counseling.